British Society of Blood and Marrow Transplantation and Cellular Therapy

an organisation for those with a professional interest in haematopoietic cell transplantation and cellular therapies


BSBMTCT Centres - UK and ROI 1st Transplant ONLY	Allografts:							Autografts:						All HSCT	CAR-T	Gene Therapy
Disease:	BM	PBSC	CB	Total Allo	BM	PBSC	CB	Total Auto	Totals	Allo	Auto	Total	Total
AML	23	600	50	673	0	1	0	1	674	10	0	10	0
ALL	30	152	16	198	0	1	0	1	199	3	102	105	0
CML	3	52	1	56	0	0	0	0	56	0	0	0	0
CLL inc. PLL	0	18	0	18	0	0	0	0	18	0	1	1	0
MDS or MDS/MPN	6	191	3	200	0	0	0	0	200	1	0	1	0
MPN	2	79	2	83	0	0	0	0	83	0	0	0	0
PCD: Multiple Myeloma	0	5	0	5	1	1663	0	1664	1669	0	7	7	0
PCD: Other	0	0	0	0	0	36	0	36	36	0	0	0	0
HL	1	39	0	40	0	186	0	186	226	0	0	0	0
NHL	3	75	0	78	0	507	0	507	585	0	431	431	0
Solid Tumours	0	1	0	1	0	127	0	127	128	0	6	6	0
BM Aplasia - SAA	36	50	0	86	0	0	0	0	86	0	0	0	0
BM Aplasia - other	9	15	1	25	0	0	0	0	25	0	0	0	0
Thalassaemia	10	4	0	14	0	0	0	0	14	0	0	0	3
Sickle Cell	22	18	0	40	0	0	0	0	40	0	0	0	1
Inborn Errors of Immunity	16	68	0	84	0	0	0	0	84	0	0	0	2
Inborn Errors of Metabolism	10	4	7	21	0	0	0	0	21	0	0	0	3
Auto-Immune Diseases	1	2	0	3	0	74	0	74	77	0	1	1	0
Others (incl. Histiocytosis)	2	16	0	18	0	5	0	5	23	0	0	0	0
Totals 1st HSCT/CAR-T/GT	174	1389	80	1643	1	2600	0	2601	4244	14	548	562	9
Non 1st HSCT/CAR-T/GT	7	66	11	84	0	162	1	163	247	0	3	3	0
Totals All HSCT/CAR-T/GT	181	1455	91	1727	1	2762	1	2764	4491	14	551	565	9
Paediatric Patients (1st HSCT/CAR-T/GT)	152	101	46	299	0	109	0	109	408	3	48	51	8
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ADDITIONAL INFORMATION:
TOTAL TRANSPLANTS IN 2024	4491
TOTALS ABOVE INCLUDE:
DLI'S	406
CORD BLOOD	92
UNRELATED DONORS	1165
RELATED DONORS: (ID SIB = 332, NON ID SIB = 229, TWIN = 1)	562
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Table 2a: 2024 UK & ROI Activity by Transplant Type and Cell Source: All HSCTs (Adults and Paediatrics).
2024	Allo ID SIB					HAPLO and Other Mismatched Related					Allo TWIN			Allo Unrelated Donor					Auto			Total	CAR-T	Total	Gene Therapy
All HSCT	BM	PBSC	CB	BM	PBSC	CB	BM	PBSC	BM	PBSC	CB	BM	PBSC	CB	Allo	Auto	HSCT	Allo	Auto	CAR-T
UK	71	259	0	17	211	0	0	1	80	982	91	1	2685	1	1712	2687	4399	14	551	565	9
ROI	2	0	0	0	1	0	0	0	11	1	0	0	77	0	15	77	92	0	0	0	0
Totals	73	259	0	17	212	0	0	1	91	983	91	1	2762	1	1727	2764	4491	14	551	565	9

Table 2b: 2024 UK & ROI Activity by Transplant Type and Cell Source: First HSCT – Paediatrics Only.
2024	Allo ID SIB					HAPLO and Other Mismatched Related					Allo TWIN			Allo Unrelated Donor					Auto			Total	CAR-T	Total	Gene Therapy
1ST HSCT	BM	PBSC	CB	BM	PBSC	CB	BM	PBSC	BM	PBSC	CB	BM	PBSC	CB	ALLO	AUTO	HSCT	ALLO	AUTO	CAR-T
UK Paeds	64	3	0	10	27	0	0	0	65	70	46	0	97	0	285	97	382	3	48	51	8
ROI Paeds	2	0	0	0	1	0	0	0	11	0	0	0	12	0	14	12	26	0	0	0	0
Total Paeds	66	3	0	10	28	0	0	0	76	70	46	0	109	0	299	109	408	3	48	51	8
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Abbreviation	Expansion	Abbreviation	Expansion
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ALL	Acute lymphoblastic leukaemia	HSCT	Haematopoietic stem cell transplantation
ALLO	Allogeneic stem cell transplant	ID SIB	Identical sibling
AML	Acute myeloid leukaemia	MDS	Myelodysplastic syndrome
AUTO	Autologous stem cell transplant	MDS/MPN	Combined myelodysplastic syndrome / Myeloproliferative neoplasm
BM	Bone marrow	MPN	Myeloproliferative neoplasm
BSBMTCT	British Society of Blood and Marrow Transplantation & Cellular Therapy	NHL	Non-Hodgkin lymphoma
CAR-T	Chimeric antigen receptor T-cell therapy	NON ID SIB	Non identical sibling
CB	Cord blood	PAEDS	Paediatric (children) patients
CLL	Chronic lymphocytic leukaemia	PBSC	Peripheral blood stem cell
CML	Chronic myeloid leukaemia	PCD	Plasma cell disorder
DLI	Donor lymphocyte infusion	PLL	Prolymphocytic leukaemia
GT	Gene therapy treatment	ROI	Republic of Ireland
HAPLO	Haploidentical donor	SAA	Severe aplastic anaemia
HL	Hodgkin lymphoma	UK	United Kingdom
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For a list of our gold, silver and bronze corporate members,

British Society of Blood and Marrow Transplantation and Cellular Therapies
Guy's Hospital, Great Maze Pond London.
SE1 9RT United Kingdom

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