Dear BSBMTCT member,

As the year rolled over into January, we waved Goodbye to 2025, and gratefully reflected on all the amazing work and achievements of our transplant and cellular therapy community. There was and is a huge amount to celebrate!

In this New Year, we are already so encouraged by the work already in motion, and the enthusiasm and optimism that a new year brings. There are lots planned for this year, and we can’t wait to be able to share and celebrate this with you. Not least, this year marks the 25^th Anniversary of our BSBMTCT Data Registry. If you have any thoughts as to how you would like to celebrate, do share them with us. The Trustees have started to think about how we celebrate our invaluable registry asset and also those who came before us and laid such strong foundations.

We are delighted to share that we recently concluded another positive BSBMTCT Meetings Grant Round enabling a number of members to attend the EBMT 2026 Congress, being held this year in Madrid during March. We received 21 applications, and were able to fund 11 individuals to attend in person with a total grant value of just under £10K. We were able to support 10 different member centres from a variety of different roles and backgrounds, including trainees, data managers, quality managers, staff nurses and clinical educators.

Despite the challenges that the new EBMT registry has presented to national registries, we are close to concluding the 16^th Edition of BSBMTCT Executive Summary of Transplant & Cellular Therapy Outcomes in UK and ROI centre reports, which we expect will be available in early February 2026. Any questions please direct them to Head of Registry, Julia Lee on julia.lee@kcl.ac.uk

We continue to update and improve our www.bsbmtct.org website, and we wanted to draw your attention to the new guidelines area on the BSBMTCT Website. The aim is to bring all the guidelines together in one place: https://bsbmtct.org/bsbmtct-guidelines/

A roundtable meeting of the UKSCSF Data Commission was held on Thursday 22^nd January 2026 to discuss the development of a UK Bespoke registry and also PTCy data collection and the monitoring of treatment impact.

UK Bespoke Registry

 As you will be aware, we have been working with the UK Stem Cell Strategic Forum (UKSCSF) Data Commission to scope out the process for the development of a new bespoke registry for the UK and Republic of Ireland. Whilst there have been vast improvements over recent years, there remain persistent challenges that we are keen to overcome. We are under no illusion that a new a new platform and system will not solve all the problems on their own. We need to look across the whole data management life cycle, considering how data is collated and submitted, what the capacity is on the ground, what tools people have, how data is verified, how we ensure data quality, how it is curated, how it is structured, accessed, analysed, interpreted, and how is it accessed and shared with those who need it. Quite deliberately the approach we are taking is not just about requirement’s definition for a new platform, as important as that is. We are looking across the whole data management lifecycle and where we need to build capacity bringing new investment. There is a lack of integration and a preponderance of data silos that stymie our collective efforts to understand the full patient journey, including who might not be referred for transplant or other treatments and why that might be the case. We presently don’t have an interface or integration with any patient-reported outcome measures or experience measures or any of the clinical trial infrastructure. Integration will be a really high priority for this initiative. Our shared ambition is to have the right data on the right platform available to the right users, and as you know, that simple statement masks huge complexity. It will be important that a new registry can adapt to meet new needs and unlock the commercial potential with the right interfaces, integration, and interoperability, so the real power of data can be magnified as well. This is a genuine community initiative led by members and partners. Do get in touch if you have any thoughts that you’d like to share.

PTCy data collection and the monitoring of treatment impact

The UK Consensus on the use of PTCy was published in November 2025 (https://bsbmtct.org/wp-content/uploads/2025/11/UK-Clinical-Community-Consensus-on-the-Emerging-use-of-PTCy-Final-version-November-2025.pdf). Next steps involve looking at registry data for past and current use of PTCy as well as surveying centre use in order to gain a baseline of understanding.

Dates for your Diary for 2026

• EBMT Congress 2026, Madrid – 22^nd March to 25^th March 2026
• BSBMTCT Scientific Day – Wednesday 6^th May 2026
• BSBMTCT Scientific Showcase – Friday 19^th June 2026
• BSBMTCT Education Day – Thursday 5^th November 2026

Our Very Best Wishes, Deborah Richardson, Eduardo Olavarria, Fiona Dignan, Harpreet Kaur, Victoria Potter, David Reynolds & Julia Lee