The BSBMTCT Data Registry holds a unique data set on the UK and Republic of Ireland (RoI) transplants, treatment and follow up. This data provides a good introduction to autologous HSCT. As you will see in Table 1 the first Autologous HSCT, in the database, took place in 1978!
Table 1: First Transplants
|FIRST AUTOLOGOUS TRANSPLANTS IN THE UK & RoI|
|DISEASE||TYPE OF HSCT||WHERE AND WHEN|
|Solid Tumour (neuroblastoma)||Autograft||Great Ormond Street February 1978|
|Hodgkin’s Lymphoma||Autograft||Royal Marsden Hospital January 1980|
|NHL||Autograft||UCL September 1981|
|Multiple Myeloma||Autograft||Royal Marsden Hospital March 1986|
|Autoimmune Disease||Autograft||Queen Elizabeth Birmingham June 1996|
If we look at the data over a 5 year period, we can see what the most common indications to treat were during that time frame for Adult and Paediatric transplants.
A total of 21,413 transplants were reported to the BSBMTCT registry over a 5-year period 2016-2020 inclusive, of which 61% were autologous transplants.
If you look at Table 2, it depicts the number of autologous transplants which took place during that time frame.
Table 2: Adult and Paediatric 2016 -2020
|AUTOLOGOUS HSCT BY YEAR FROM 2016 TO 2020|
Depicted in Table 3 are all malignant and non malignant indications to treat for the same period 2016 – 2020.
Table 3: Malignant and Non Malignant Indications
|AUTOLOGOUS HSCTs FROM 2016 TO 2020 INCLUSIVE|
In the following topics this data has been broken down into more detail looking more closely at the different diseases that were treated with an autologous transplant and into adult and paediatric categories.