BSBMTCT AUTOLOGOUS HSCT DATA

The BSBMTCT Data Registry holds a unique data set on the UK and Republic of Ireland (RoI) transplants, treatment and follow up.  This data provides a good introduction to autologous HSCT.  As you will see in Table 1 the first Autologous HSCT, in the database, took place in 1978!

Table 1: First Transplants

                                                             FIRST AUTOLOGOUS TRANSPLANTS IN THE UK & RoI  
DISEASETYPE OF HSCTWHERE AND WHEN
Solid Tumour (neuroblastoma)AutograftGreat Ormond Street February 1978
Hodgkin’s LymphomaAutograftRoyal Marsden Hospital January 1980
NHLAutograftUCL September 1981
Multiple MyelomaAutograftRoyal Marsden Hospital  March 1986
Autoimmune DiseaseAutograftQueen Elizabeth Birmingham June 1996

If we look at the data over a 5 year period, we can see what the most common indications to treat were during that time frame for Adult and Paediatric transplants.  

A total of 21,413 transplants were reported to the BSBMTCT registry over a 5-year period 2016-2020 inclusive, of which 61% were autologous transplants.

 If you look at Table 2, it depicts the number of autologous transplants which took place during that time frame.

Table 2: Adult and Paediatric 2016 -2020

AUTOLOGOUS HSCT BY YEAR FROM 2016 TO 2020
YEAR20162017201820192020TOTAL
ADULT2526253825952675192812262
PAEDIATRIC142159156152149758
TOTAL2668269727512827207713030

Depicted in Table 3 are all malignant and non malignant indications to treat for the same period 2016 – 2020.

Table 3: Malignant and Non Malignant Indications

  AUTOLOGOUS HSCTs FROM 2016 TO 2020 INCLUSIVE
TYPEADULTPAEDIATRIC
NON-MALIGNANT29913
MALIGNANT11844736
TOTAL12143749

In the following topics this data has been broken down into more detail looking more closely at the different diseases that were treated with an autologous transplant and into adult and paediatric categories.

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